Moderna Coronavirus Vaccine Phase 3 on 30,000 Volunteers

3 min readJul 27, 2020

Moderna Coronavirus vaccine phase 3 on 30,000 volunteers has started by the U.S. government.

Volunteers won’t know if they’re getting the real shot or a simulated version. After two doses, scientists will closely track which group experiences more shots as they go about their daily routines, especially in areas where the virus still is spreading variously.

This vaccine is developed by the National Institutes of Health and Moderna Inc.

Moderna said the vaccination was done in Savannah, Georgia, the first site to get underway among more than seven dozen trial sites dispersed around the country.

Several other vaccines were made by China and by Britain’s Oxford University earlier this month and began smaller final-stage tests in Brazil and other hard-hit countries. But the U.S. requires its own tests of any vaccine that might be used in the country.

Moderna Coronavirus vaccine phase 3 final test

The extensive studies aren’t just to test. If the shots work they’re needed to check each possible vaccine’s safety and following the same study rules will let scientists eventually compare all the shots.

Dr. Larry Corey says that’s a stunning number of people needed to roll up their sleeves for science. But in recent weeks more than 150,000 Americans filled out an online registry signaling interest a virologist with the Fred Hutchinson Cancer Research Institute in Seattle, who helps oversee the study sites.

“These trials need to be multigenerational, they need to be multiethnic, they need to reflect the diversity of the United States population,” Corey told a vaccine meeting last week. He emphasized that it’s especially important to ensure enough Black and Hispanic participants as those populations are hard-hit by COVID-19.

It normally takes years to create a new vaccine from scratch, but scientists are setting speed studies this time around, impelled by the knowledge that vaccination is the world’s best hope through the pandemic.

Covid-19 vaccine first tests

The coronavirus wasn’t even known to exist before late December, and vaccine makers sprang into action Jan. 10 when China shared the virus’ genetic order.

Just 65 days later, in March, the NIH-made vaccine was tested on people. The first receiver is encouraging others to be a volunteer now.

There’s still no guarantee that the experimental vaccine will really protect. If everything goes right with the final studies, it still will take months for the first data to run in from the Moderna test.

Governments around the world are trying to save millions of doses of those leading candidates so if and when regulators approve one or more vaccines, immunizations begin immediately. But the first available doses will be apportioned, probably reserved for people at the highest risk from the virus.

“We’re optimistic, cautiously optimistic” that the vaccine will work and that “toward the end of the year” there will be data to prove it, Dr. Stephen Hoge, president of Massachusetts-based Moderna said last week.

“I don’t know what the chances are that this is the exact right vaccine. But thank goodness that there are so many others out there battling this right now,” she said.

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Originally published at on July 27, 2020.




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